The best summary so far…

[except for the story about the Sky News Documentary - I checked by watching it and did not see a mention of DEFUSE. The documentary must have been in the can long before anyway].
@maiahibbett @fastlerner

The paradigm has now shifted - and once scientists have digested it they shall start coming together to express their concerns. That's what responsible science should be.

Martin Wikelski, a director at the Max Planck Institute of Animal Behavior in Germany:

“The work describes generating full-length bat SARS-related coronaviruses that are thought to pose a risk of human spillover. And that’s the type of work that people could plausibly postulate could have led to a lab-associated origin of SARS-CoV-2,” said Jesse Bloom, @jbloom_lab

“We now have evidence that, in early 2018, they had pitched inserting novel cleavage sites into novel SARS-related viruses in their lab,” said Chan. “This definitely tips the scales for me. And I think it should do that for many other scientists too.” @Ayjchan

We already had the mother of all conflicts of interest with Peter Daszak - something that nobody would deny today.

Silence is no option. If questions should be raised after reading the DEFUSE proposal, then they need to be raised.